Jo Koy: My brain always wants to think funny Margot Robbie talks about filming ‘Bombshell’s’ disturbing sexual harassment scene LATEST STORIES It’s too early to present Duterte’s ‘legacy’ – Lacson MOST READ Photo by Tristan Tamayo/ INQUIRER.netFor new Phoenix coach Louie Alas, his first day on the job couldn’t get any better.The seasoned mentor was satisfied with the Fuel Masters’ haul in the 2017 PBA Rookie Draft on Sunday.ADVERTISEMENT Jake says relationship with Shaina ‘goes beyond physical attraction’ Sports Related Videospowered by AdSparcRead Next Carpio hits red carpet treatment for China Coast Guard PLAY LIST 02:14Carpio hits red carpet treatment for China Coast Guard02:56NCRPO pledges to donate P3.5 million to victims of Taal eruption00:56Heavy rain brings some relief in Australia02:37Calm moments allow Taal folks some respite03:23Negosyo sa Tagaytay City, bagsak sa pag-aalboroto ng Bulkang Taal01:13Christian Standhardinger wins PBA Best Player award Drop in draft blessing in disguise for Davon Potts as he joins Aces Kiss-and-tell matinee idol’s conquests: True stories or tall tales? Jake says relationship with Shaina ‘goes beyond physical attraction’ “That’s the kind of players we want. What we need here is to play aggressive for the whole 48 minutes,” he said, likening his approach to how he handled his last head coaching job in Letran. “You can’t go wrong when you’re aggressive, but what we need is controlled aggression.”Alas said Phoenix already has the tools to compete in the league with the trio of Matthew Wright, Jeff Chan, and JC Intal in tow, but he’s hoping to get significant contributions for their rookies.“I believe we are three good pieces away from contending. Hopefully, the ones we picked will fill up the roles we expect from them,” he said.Looking back to the dismal at the franchise’s dismal had last season, Alas is putting those performances behind with Phoenix hell-bent on making an impact this year.“We mean business,” he vowed. “Everything that happened last year will not happen again.”ADVERTISEMENT “Everyone who we projected and expected to fall on us, we got all of them,” he said.Alas tapped Jason Perkins as Phoenix’s fourth overall pick before claiming Sidney Onwubere eighth in the first round.FEATURED STORIESSPORTSRedemption is sweet for Ginebra, Scottie ThompsonSPORTSMayweather beats Pacquiao, Canelo for ‘Fighter of the Decade’SPORTSFederer blasts lack of communication on Australian Open smogThe Fuel Masters continued to stockpile on the upstarts, taking big man Jayson Grimaldo, shooter Wilson Baltazar, and guards Dan Sara and JK Casiño in the succeeding rounds.Alas put a premium on hardwork when making their picks and that was the common denominator among Phoenix’s prospects. OSG plea to revoke ABS-CBN franchise ‘a duplicitous move’ – Lacson Steam emission over Taal’s main crater ‘steady’ for past 24 hours Coco’s house rules on ‘Probinsyano’ set Don’t miss out on the latest news and information. View comments
One might think that 154 years after Darwin’s book about it, natural selection would be empirically obvious. The journal Nature went on a search for it in DNA.Nature‘s piece, “Evolutionary Genomics: Detecting Selection” begins with hopes and worries:Advances in population genetics and genome sequencing have made it possible to identify anonymous fragments of DNA that have undergone selection. This yields some evolutionary answers, and a panoply of puzzles.Two things must be clarified before detecting natural selection. One is that artificial selection has nothing to do with it. Artificial selection is intelligently designed for a purpose; natural selection, by contrast, is unguided and purposeless. Even survival fails as a purpose; it’s only a consequence of selection, not a goal of selection. The other is that natural selection is more than variation. To differentiate itself from creationism, natural selection has to overcome small changes within a population that creationists willingly acknowledge help an organism adapt. Evolutionists need to demonstrate innovation, an undirected change providing new functional information. A mutation that produces “more of the same” effects, like a change in enzyme production, does not qualify.With that in mind, what did the Nature article find in its selection hunt? The authors acknowledged the “awesome power of artificial selection” directed by the mind of man, such as in dog breeding, but claimed that dogs and humans have been partners in natural selection for 10,000 years in a case of “parallel evolution.” They praised a recent paper in population genetics that “promises to revolutionize evolutionary biology, by challenging us to detect traits affected by evolution on the basis of genotype rather than an organism’s characteristics, or phenotype.” Then they praised two other papers that “rise to this challenge and show how hypotheses about an adaptive human genotype can be tested in controlled experiments.” Sounds impressive. But is this something new? What’s gone on in the past 154 years of research on natural selection? It must not have been very revolutionary.Together, the three papers are a wonderful intersection between genomics, population science and experimental genetics — a synergy that has tremendous potential for teaching us more about how and why organisms evolve.Unfortunately, the evidence cited in the first paper concerns genetic changes found between wolves and domestic dogs. Even the staunchest creationists put those two animals within the same created kind. The genetic changes, moreover, were in the “more of the same” category – enhanced ability to digest starch, presumably from crumbs dropped from the dog owners’ tables. Nevertheless, the authors were ecstatic that dogs and humans both produce more starch-digesting enzymes: “the same molecular mechanism has acted on similar genes in different species exposed to the same dietary pressure — a striking example of parallel evolution.”The other two papers merely found evidence of “selective sweeps” without tying the changes to phenotypic change. “Even when causal relationships seem obvious, caution is warranted,” the authors warned, noting a case with ambiguous results. Is detection of natural selection in human populations even possible? “Classical genetic studies are the optimal way to establish causal relationships, but in many cases these are impossible because the appropriate populations do not exist.” The third paper invented a “model organism” to tease out evidence of natural selection. Its researchers concluded that a mutation in East Asians produces thicker hair and more sweat glands; they verified that effect in mice (see 2/19/13, last section). But that’s another example of “more of the same” variation; people already had sweat glands and hair, and so did mice.Remarkably, this article, poised to showcase the power of natural selection, ended with ignorance:Kamberov and colleagues’ study is an exceptional example of experimental genetics, but does it provide, as the authors suggest, a general framework for assessing candidate adaptive mutations? Genetically altered mice are a powerful experimental tool, but the extent to which recent positive selection in humans acts on pathways and amino-acid residues that have been conserved across mammalian evolution is uncertain. More importantly, it is often not clear how to investigate positively selected genomic regions for which the target gene, let alone its action, is unknown. And so a major challenge for population genomics remains the construction of meaningful null hypotheses. As Charles Darwin, the best known evolutionary biologist, once said, “It is always advisable to perceive clearly our ignorance”.So even though the paper they praised was “an exceptional example” of looking for natural selection, the authors of this article worried its conclusions are uncertain. Worse, (“more importantly”), it’s not even clear how to look for selection in genomic regions where the action is unknown. How does a researcher compare the findings with a null hypothesis—a baseline hypothesis that posits no effect from the cause-when “meaningful null hypotheses” are lacking?That’s why the summary of this triumphantly-titled article spoke of “some evolutionary answers, and a panoply of puzzles.” Even the answers, though, wouldn’t impress a creationist: no clear evidence of positive selection toward new functional information was presented. One can only hope the authors of all these papers are following Darwin’s advice to perceive clearly their ignorance.And they call creationists ignoramuses. OK, show us, Darwinites. Darwin believed people have bacteria ancestors. All the advances beyond bacteria for every species on earth—be they wings, eyes, or brains—are supposed to be the result of natural selection. Yet here it is, 154 years after the Origin, and evolutionists still cannot show any example in the genes bigger than starch digestion in dogs, or thicker hair and more sweat glands in certain humans (all interfertile members of the same species, Homo sapiens). The authors admit the studies are unclear. It’s appalling that the sole theory allowed to be presented in public school science classes is ignorant, not only of examples, but of ways to test them. What hath evolutionary theory wrought? A panoply of puzzles! Schools are teaching ignorance!If evolutionists do not perceive clearly their ignorance, those of us who do perceive it need to hold it up to their faces. We can quote Darwin for support: “It is always advisable to perceive clearly [y]our ignorance.”(Visited 17 times, 1 visits today)FacebookTwitterPinterestSave分享0
Amanda Razani Follow the Puck Why IoT Apps are Eating Device Interfaces Small Business Cybersecurity Threats and How to… Internet of Things Makes it Easier to Steal You… With Fashion Week coming up soon, Rebecca Minkoff brand is planning to make a ripple by integrating the Internet of Things with its handbags.Rebecca Minkoff has announced the launch of its connected handbags that will be available at an upcoming pop-up shop at the Grove in Los Angeles. There will be a small supply of only 10 limited edition bags for purchase. These digitally enhanced bags will be equipped with hang tags that will give entry into the spring/summer 2017 runway once scanned. Tech lovers may want to give some serious thought to these bags, labeled the #AlwaysOn Midnighter style.See Also: IoT means never losing your bag againThe brand plans to connect 10 billion accessories and articles of clothing during the next three years, as part of its #BornDigital campaign.What’s next in connected fashion?“We know that all products in the future will have a digital life as part of the Internet of Things,” states Uri Minkoff, co-founder and CEO of the brand. “Rebecca Minkoff wants to be first in letting our customers access this new world of experiences, content and services digitally by interacting with our physical designs. Most fashion brands lose sight of their products and customers; this technology now allows us to directly connect with shoppers through our products after purchase. We’re incredibly excited by a born digital future, and you’ll be seeing it integrated across many more of our products later in the year.”With the world of IoT growing and expanding to all sorts of products, more companies are wanting in on this popular trend. Rebecca Minkoff has its foot in the door now, and it won’t be surprising if more brands follow suit in the near future. Tags:#Fashion Week#handbags#Internet of Things#IoT#rebecca minkoff Related Posts
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There is nothing unusual about this photo identity card, perfectly legal and valid for the London Olympics. But look at it closely and you will see Janardhan Gehlot, secretary of the Indian Kabaddi Federation, wearing the card of the secretary general of the Indian Olympic Association.At a time when there has been a huge uproar over one Madhura Nagendra spoiling the Indian march past at the opening ceremony, Gehlot has misrepresented his details to the LOCOG (London Organising Committee). Sources told Mail Today that as the IOA got only four cards for the Olympics, secretary general Randhir Singh has “given” his card to Gehlot. Randhir got accreditation from the International Olympic Committee (IOC), where he is a member.If the National Olympic Committee (NOC) can misrepresent facts to an Olympic host, one wonders what’s wrong in Madhura getting a card for herself, though it did cause a huge scare. With the IOA elections due in October, it is clear Gehlot finds himself in favour with Randhir, as more than two factions will be battling it out. On Monday, when Gagan Narang was shooting in the air rifle final, Gehlot was wearing this card and it was photographed by this reporter. MAIL TODAY has learnt that Gehlot gets the “privileges” in London which a secretary general of an NOC is entitled to.
A workshopper assisted CIO Tomiaki Tamura to scoop Passion Fruit Sorbet for desert. Chef Ali Sadiqi planned the menu for the dinner following the concert which included: Chilled Avocado Soup, ThaiLemongrass and Mussel Soup, Southwest Chicken Salad, Dilled Seafood Salad, Curried Red Lentils with Raisinsand Capers, Indonesian Tempeh with Peanuts and Pak Choy, and Arcosanti Bakery Pesto Swirl Bread. Planning Department Manager Nadia Begin and Paolo Soleri chat with a concert-goer.Also pictured, Site Coordinator Mary Hoadley. August 17, 2001Every summer Arcosanti hosts The Young Composers Workshop – a chance for youngcomposers to work withprofessional musicians culminating with a concert in the Colly Soleri Music Center. Pictured: The California E.A.R.Unit – who have been the “ensemble-in-residence for the workshop” since 1995.[Photos and text by: Jennifer Thornton] Earlier in the day, Workshoppers helped the cafe to prepare hors d’oeuvres for the event. Workshoppers Mary and Julia served appetizers during intermission.
Tags: FOIA Categories: Reilly News State Rep. John Reilly of Oakland Township says he supports bipartisan legislation introduced today to make state government more transparent.“This is another sign of the House’s commitment to be more accountable and accessible to the people of Michigan,” Reilly said.Reilly joined colleagues in the announcement of the bill package to make Michigan’s governor and lieutenant governor subject to the Freedom of Information Act. The proposal also calls for a similar disclosure requirement for state representatives and senators, called the Legislative Open Records Act.“I believe government should be held accountable to the people they serve,” he said.Michigan is one of just two states where public records disclosure does not apply to the governor’s office.The Legislative Open Records Act would exempt some records, including letters to and from people in the lawmaker’s district, human resources files and ongoing legislative investigations or lawsuits.Today’s bill package introduction comes in the wake of the House’s recent announcement that its website now includes the salary information of every representative and employee, another move toward increased transparency.### 01Feb Reilly on board with new state government transparency initiative