As a matter of fact, rumors are circulating that the Wii 2 is expected to be announced as soon as the next E3. The rumors, which are based on sources close to the company, according to those who are spreading them, would bring the Wii 2 to a level similar to that of an Xbox 360 or a PS3. Though, some bloggers have speculated that this would be a contradiction to the accessible to all image that the original Wii has created. That would leave the Wii 2 fighting with the Xbox 360 and PS3 for a share of hardcore gamers market.Specific rumors swirl around the idea of the console having a Blu-ray drive, because those disks can hold the amount of data that Nintendo would need to launch their HD titles on a larger scale.This comes only days after the rumor that Wii is ready to go in for a price drop, to $149.99, on May 15. If the Wii 2 is to be announcement by Nintendo during E3 this year, then the price drop would make a lot of sense. No real information about possible release dates or the cost of the device is available at this time, but If the rumors pan out the new Nintendo Wii would be launched in 2012. That type of lead time will give developers time to create games to come with the console. Nintendo recently released a new version of their hand held DSi console, called the 3DS that features 3D graphics. Nintendo’s ‘Revolution’ becomes ‘Wii’ Explore further Citation: Wii 2 goes HD? (2011, April 15) retrieved 18 August 2019 from https://phys.org/news/2011-04-wii-hd.html (PhysOrg.com) — Is Nintendo working on a high-definition console called the Wii 2? That is the big question flying around the world of gaming today. Wii © 2010 PhysOrg.com This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
Citation: New carbon allotrope could have a variety of applications (2011, April 22) retrieved 18 August 2019 from https://phys.org/news/2011-04-carbon-allotrope-variety-applications.html (PhysOrg.com) — Carbon comes in many different forms, and now scientists have predicted another new form, or allotrope, of carbon. The new form of carbon, which they call T-carbon, has very intriguing physical properties that suggest that it could have a wide variety of applications. The scientists, Xian-Lei Sheng, Qing-Bo Yan, Fei Ye, Qing-Rong Zheng, and Gang Su, from the Graduate University of Chinese Academy of Sciences in Beijing, China, have published their study on the first-principles calculations of T-carbon in a recent issue of Physical Review Letters.Allotropes are formed when the atoms in a substance that contains only one type of atom are arranged differently. Although many substances have multiple allotropes, carbon has the greatest number of known allotropes. The three best-known carbon allotropes are amorphous carbon (such as coal and soot), graphite, and diamond. Since the 1980s, scientists have been synthesizing newer allotropes, including carbon nanotubes, graphene, and fullerenes, all of which have had a significant scientific and technological impact.With more recent advances in synthetic tools, scientists have been investigating a wide variety of new – and sometimes elusive – carbon allotropes. In light of these investigations, Sheng, et al., write in their study that it appears that we might be entering the era of carbon allotropes.Here, the scientists explained how to obtain a new carbon allotrope by substituting each carbon atom in diamond with a carbon tetrahedron (hence the name “T-carbon”). They were inspired by the substitution of each carbon atom in methane with a carbon tetrahedron, which forms tetrahedrane.“[Our study] adds a possible new allotrope of carbon with amazing properties,” Su told PhysOrg.com. “T-carbon has bond angles different from graphite and diamond, but the interesting structure is still quite stable and has the same group symmetry as diamond, thereby widening people’s vision and knowledge on carbon bonding.”Each unit cell of the T-carbon structure contains two tetrahedrons with eight carbon atoms. As the scientists’ calculations showed, T-carbon is thermodynamically stable at ambient pressure and is a semiconductor. T-carbon is one-third softer than diamond, which is the hardest known natural material. The new carbon allotrope also has a much lower density than diamond, making it “fluffy.” The structure of the new carbon allotrope, T-carbon, is shown from different directions. T-carbon is obtained by replacing each carbon atom in diamond with a carbon tetrahedron. Image credit: Sheng, et al. ©2011 American Physical Society. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Explore further Copyright 2010 PhysOrg.com. All rights reserved. This material may not be published, broadcast, rewritten or redistributed in whole or part without the express written permission of PhysOrg.com. Structure of new form of super-hard carbon identified The scientists also calculated that T-carbon has large interspaces between atoms compared to other forms of carbon, which could make it potentially useful for hydrogen storage. In addition, the unique physical properties of this new carbon allotrope make it a promising material for photocatalysis, adsorption, and aerospace applications.“We believe that, if obtained, T-carbon is so fluffy that it can be used to store hydrogen, lithium, and other small molecules for energy purposes,” Su said. “It can be used as photocatalysis for water-splitting to generate hydrogen, or as an adsorption material for environmental protection. As it has very low density but a high modulus and hardness, it is quite suitable for aerospace materials, sports materials like a tennis racket, golf club, etc., and cruiser skin, and so forth.”The scientists also noted that T-carbon could have astronomical implications as a potential component of interstellar dust and carbon exoplanets.“There is a long-standing puzzle in astronomy known as the ‘carbon crisis’ in interstellar dust,” Su said. “Observations by the Hubble telescope revealed that the carbon budget in dust is deep in the red, and there is not sufficient carbon in dust to account for the light distortions.”In addition, the exoplanet WASP-12b has recently been found to have a large amount of carbon, making it the first carbon-rich exoplanet ever discovered. Since the structure of the carbon in WASP-12b is still unclear, T-carbon might also be one of possible candidates for this carbon planet.To investigate T-carbon further, the researchers would like to synthesize the new allotrope in the lab, although they say that this would likely be very difficult.“A synthesis of T-carbon in the lab poses a great challenge for materials scientists and chemists,” Su said. “We suggest the following ways: using the CVD technique under a negative pressure environment; detonation on diamond or graphite; crystallization of amorphous tetragonal carbon; or stretching cubic diamond under extremely large strength.” More information: Xian-Lei Sheng, et al. “T-Carbon: A Novel Carbon Allotrope.” Physical Review Letters 106, 155703 (2011). DOI: 10.1103/PhysRevLett.106.155703
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. (PhysOrg.com) — Less than a decade after launching their first astronaut into space, the China Manned Space Engineering Office announced in a news conference this week their plans to build and develop a 60-ton space station with three capsules and a cargo spacecraft. Citation: China announces Space Station plans (2011, April 28) retrieved 18 August 2019 from https://phys.org/news/2011-04-china-space-station.html Explore further Image: China Daily © 2010 PhysOrg.com More information: via China Daily China tests space station module to launch in 2011 The space station, much smaller than the International Space Station which is 419 tons, will be comprised of three different modules. The core module will be 18.1 meters long, a diameter of 4.2 meters and will have a launch weight of between 20 and 22 tons. This module will be launched first, with the experiment modules launched to dock later. The experiment modules will be 14.4 meters long and will have the same launch weight and diameter as the core.The cargo spacecraft will have a maximum diameter of 3.35 and its launch weight will be less than 13 tons. This craft will be used to transport supplies and lab equipment to and from the space station.Their current five year plan has them launching an unmanned module and spacecraft later this year to work on their docking technology, with the hopes of manned missions sometime next year.Initial plans for the space station and its name were “Tiangog,” meaning heavenly palace. However, China’s Manned Space Engineering Office officials have announced they are turning to the public to submit names for the station and the cargo ship. Names for the cargo ship must be submitted by May20th and they plan to announce the final name sometime in June. Names for the space station can be submitted until July 25, with the name being chosen by the end of September.With the development of this space station, China is also hoping to increase their international exchanges in the world’s space programs. Everything within their station will be compatible with that of the International Space Station and they are welcoming all space science researchers to participate.According to reports, China is also hoping to make its first landing on the moon within the next two years and the hope is to have an astronaut on the moon by 2025.
Citation: Nanoparticle boosted T-cells take on cancer (2011, May 5) retrieved 18 August 2019 from https://phys.org/news/2011-05-nanoparticle-boosted-t-cells-cancer.html This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. More information: Therapeutic cell engineering with surface-conjugated synthetic nanoparticles, Nature Medicine 16, 1035–1041 (2010) doi:10.1038/nm.2198AbstractA major limitation of cell therapies is the rapid decline in viability and function of the transplanted cells. Here we describe a strategy to enhance cell therapy via the conjugation of adjuvant drug–loaded nanoparticles to the surfaces of therapeutic cells. With this method of providing sustained pseudoautocrine stimulation to donor cells, we elicited marked enhancements in tumor elimination in a model of adoptive T cell therapy for cancer. We also increased the in vivo repopulation rate of hematopoietic stem cell grafts with very low doses of adjuvant drugs that were ineffective when given systemically. This approach is a simple and generalizable strategy to augment cytoreagents while minimizing the systemic side effects of adjuvant drugs. In addition, these results suggest therapeutic cells are promising vectors for actively targeted drug delivery.via Newscienctist Nanoparticle-decorated cells power novel approach to cancer therapy T-cells are a group of white blood cells that works with the body’s immune system. When cancerous cells are found within the body, T-cells swarm around to try and destroy the cancer. However, many tumors will emit a chemical which works to weaken the T-cells, allowing the cancer to continue to grow.Irvine’s team discovered that they were able to attach 100 nanoparticle capsules to a T-cell without affecting its function. The team then filled these capsules with interleukins. Interleukins are naturally made in the immune system and work as system regulators by keeping the T-cells fighting. By adding the additional interleukins, they increase the ability for the T-cells to push forward and attack the cancerous cells.The team then injected these boosted T-cells into mice who were infected with bone and lung cancer. The T-cells immediately swarmed the cancerous cells and were able to stay functional for much longer than the traditional T-cells. In addition, mice treated with regular T-cells died from tumors within a month, while those treated with the boosted cells were had improving health.Because these T-cells are being modified by the nanoparticles, there is no need for them to be genetically modified which is complex and costly. This process also has the potential to speed up clinical trials. (PhysOrg.com) — According to a study in Nature, Darrell Irvine from the Massachusetts Institute of Technology and his team members have found a way to boost the natural immune system when it comes to fighting cancer by arming them with interleukin-filled nanoparticles. Explore further © 2010 PhysOrg.com
Deadly Australian horse virus found in dog Overview of a Theiler’s disease outbreak. Credit: (c) PNAS, doi: 10.1073/pnas.1219217110 This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. First identified in 1919, Theiler’s Disease is associated with the use of blood products. Many outbreaks have occurred in North America and Europe after horses received plasma or serum to protect them from contagious diseases, such as anthrax or encephalitis, or toxins, such as botulism or tetanus. Because of this, veterinary researchers have long believed that an infectious agent or toxin that contaminates the blood supply causes the disease. However, nobody had ever identified such a contaminant. Ganem and his colleagues studied horses that contracted Theiler’s Disease after receiving botulinum antitoxin. Out of 17 horses that received the same antitoxin after possible exposure to botulism, 8 developed Theiler’s Disease. To investigate the possibility that a virus in the antitoxin had caused the disease, the team extracted RNA from two of the horses that contracted it and from the antitoxin itself. They used next-generation sequencing to identify a previously unknown virus, which they designated “Theiler’s Disease-associated virus” (TDAV). The researchers found TDAV in all eight horses that developed hepatitis and in the horse, from another farm, that provided the antitoxin. TDAV is a member of the Flaviviridae family of viruses, which also includes the viruses that cause hepatitis C, yellow fever and dengue fever in humans. Amy Kistler, who participated in the research, believes that nobody identified TDAV before because it does not closely resemble any previously known viruses. It shares only 35.3% amino acid identity with its closest relative, a virus known as GB virus D.Horses on the same farm that received a different antitoxin or no antitoxin at all never contracted the disease, indicating that horse-to-horse contact is not a means of transmission.An epidemiological survey of horses on that farm and two other farms also revealed an association between exposure to TDAV-positive antitoxin and development of Theiler’s Disease. The team concedes that further research is required. They have not yet determined where TDAV originates. In addition, TDAV may not be the only cause of Theiler’s Disease; five different viruses cause human hepatitis. More information: Identification of a previously undescribed divergent virus from the Flaviviridae family in an outbreak of equine serum hepatitis, Published online before print March 18, 2013, doi: 10.1073/pnas.1219217110 AbstractTheiler’s disease is an acute hepatitis in horses that is associated with the administration of equine blood products; its etiologic agent has remained unknown for nearly a century. Here, we used massively parallel sequencing to explore samples from a recent Theiler’s disease outbreak. Metatranscriptomic analysis of the short sequence reads identified a 10.5-kb sequence from a previously undescribed virus of the Flaviviridae family, which we designate “Theiler’s disease-associated virus” (TDAV). Phylogenetic analysis clusters TDAV with GB viruses of the recently proposed Pegivirus genus, although it shares only 35.3% amino acid identity with its closest relative, GB virus D. An epidemiological survey of additional horses from three separate locations supports an association between TDAV infection and acute serum hepatitis. Experimental inoculation of horses with TDAV-positive plasma provides evidence that several weeks of viremia preceded liver injury and that liver disease may not be directly related to the level of viremia. Like hepatitis C virus, the best characterized Flaviviridae species known to cause hepatitis, we find TDAV is capable of efficient parenteral transmission, engendering acute and chronic infections associated with a diversity of clinical presentations ranging from subclinical infection to clinical hepatitis. Journal information: Proceedings of the National Academy of Sciences © 2013 Phys.org (Phys.org) —Theiler’s Disease is one of the most common causes of equine hepatitis. Death rates in horses that develop symptoms range between 50 and 90 percent. Although veterinarians have known about Theiler’s Disease for almost 100 years, until now, scientists have been unable to determine its cause. In a paper published in the Proceedings of the National Academy of Sciences, Donald Ganem and his colleagues at the Novartis Institute for Biomedical Research and Cornell University College of Veterinary Medicine report they have identified the virus that probably causes the disease. Citation: Researchers identify virus that causes horse hepatitis (2013, March 19) retrieved 18 August 2019 from https://phys.org/news/2013-03-virus-horse-hepatitis.html Explore further
Emergent population of Aulacomnium turgidum from beneath the Tear Drop Glacier, Sverdrup Pass, Ellesmere Island, Nunavut. Credit: Catherine La Farge. The research team ventured to the Canadian Arctic Archipelago to see what changes were occurring in the Arctic due to global warming—the Teardrop Glacier on Ellesmere Island in Nunavut, they note, has retreated more than 650 feet over the past several hundred years. Just next to the glacier’s edge, the team found some green growth among clumps of exposed dead plant material that had been under the ice for centuries. Intrigued, they collected some samples and brought them back to their lab for study. Emergent population of Aulacomnium turgidum from beneath the Tear Drop Glacier, Sverdrup Pass, Ellesmere Island, Nunavut. Credit: Catherine La Farge. Journal information: Proceedings of the National Academy of Sciences © 2013 Phys.org Explore further The team put 24 cultures in an ideal environment and found that 11 of them began to grow, representing four distinct taxa. The plants, known as bryophytes—moss, lichen, liverworts, etc—don’t have vascular tissue to pump fluids, a property that helps them survive in very cold climates. Carbon dating of the samples showed that the plants had been living approximately 400 to 615 years ago—a time just before the Little Ice Age (1550-1850). Byrophytes have another property, called totipotency that allows any cell of the plant to reproduce and grow into a whole new plant. The findings dispel the common belief that land exposed by melting glaciers becomes populated by new plant growth exclusively via seeds or spores carried by the wind. Instead, some plants lying frozen beneath the ice are apparently able to survive and begin growing again when the environment changes. This suggests that Earth scientists will have to take a new look at models meant to portray how ecosystems recover from glaciers after they retreat. In vitro culture of Aulacomnium turgidum regenerated from emergent Little Ice Age population beneath the Tear Drop Glacier, Sverdrup Pass, Ellesmere Island, Nunavut. Credit: Catherine La Farge More information: “Regeneration of Little Ice Age bryophytes emerging from a polar glacier with implications of totipotency in extreme environments,” by Catherine La Farge, Krista H. Williams, and John H. England. PNAS, 2013. To be available at www.pnas.org/cgi/doi/10.1073/pnas.1304199110AbstractAcross the Canadian Arctic Archipelago, widespread ice retreat during the 20th century has sharply accelerated since 2004. In Sverdrup Pass, central Ellesmere Island, rapid glacier retreat is exposing intact plant communities whose radiocarbon dates demonstrate entombment during the Little Ice Age (1550–1850 AD). The exhumed bryophyte assemblages have exceptional structural integrity (i.e., setae, stem structures, leaf hair points) and have remarkable species richness (60 of 144 extant taxa in Sverdrup Pass). Although the populations are often discolored (blackened), some have developed green stem apices or lateral branches suggesting in vivo regrowth. To test their biological viability, Little Ice Age populations emerging from the ice margin were collected for in vitro growth experiments. Our results include a unique successful regeneration of subglacial bryophytes following 400 y of ice entombment. This ﬁnding demonstrates the totipotent capacity of bryophytes, the ability of a cell to dedifferentiate into a meristematic state (analogous to stem cells) and develop a new plant. In polar ecosystems, regrowth of bryophyte tissue buried by ice for 400 y signiﬁcantly expands our understanding of their role in recolonization of polar landscapes (past or present). Regeneration of subglacial bryophytes broadens the concept of Ice Age refugia, traditionally conﬁned to survival of land plants to sites above and beyond glacier margins. Our results emphasize the unrecognized resilience of bryophytes, which are commonly overlooked vis-a-vis their contribution to the establishment, colonization, and maintenance of polar terrestrial ecosystems.Press release How the ice ages ended The researchers note that plants aren’t the only type of life being exposed by melting glaciers—cyanobacteria and green terrestrial algae have also been spotted, some of which haven’t ever been seen before. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Citation: Researchers find 400 year old Ice Age plants in Arctic able to grow anew as glaciers retreat (2013, May 28) retrieved 18 August 2019 from https://phys.org/news/2013-05-year-arctic-anew-glaciers-retreat.html (Phys.org) —A team of researchers from the University of Alberta led by, Catherine La Farge, has found that mosses and liverworts covered by ice over 400 years ago and now exposed due to glacial melting, are able to start growing again. In their paper published in the journal Proceedings of the National Academy of Sciences, the team describes how carbon dating showed the plants to be from a time just prior to the Little Ice Age. Catherine La Farge gets an up-close look at bryophytes uncovered by the retreating Teardrop Glacier on Ellesmere Island in the Canadian Arctic Archipelago.
© 2014 Phys.org PIs are typically listed as the lead on proposals and when they are male, the researchers report, the chances are greater that their project will be approved. In their paper uploaded to the preprint server arXiv (soon to be published in Publications of the Astronomical Society of the Pacific) the researchers note that efforts have been made to get rid of gender bias, but there still appears to be room for improvement.It’s not easy getting time on Hubble, researchers must form teams and then come up with something relevant and interesting to study. After that, they have to write a proposal and submit it to STScI—after review the proposal is accepted or rejected—only a quarter of those submitted wind up getting telescope time. Unfortunately, it seems that the odds are diminished even further if the PI is female. Not by much, the researchers report, just by four or five projects each proposal cycle—but that’s enough to cause concern, especially in light of the fact that program officials have been trying to eliminate such perceived bias. They’ve tried giving talks to reviewers, to explain the problem in the hopes it will cause them to be less biased, they’ve tried moving team members name to the back page—and even using just an initial for the first name of the PI. None of its worked, and the researchers don’t know why. They acknowledge that it’s possible that female led proposals are simply not as interesting or as well thought out or written, in some cases, but also point out that very few if any proposals are written by only female teams—they’re all filled with both men and women. Gender appears to only play a role for the PI.The researchers have been studying the problem for two years, and are still mystified by the lack of change—they note that the problem is more pronounced when the PI is more senior—the difference is smaller for recent graduates, suggesting that the problem may solve itself given time. They also note that Hubble isn’t the only program with the problem—some small studies have suggested that female led proposals meet with less success on other observatories as well. Gender bias found in how scholars review scientific studies Explore further Citation: Hubble team finds male led teams still getting more telescope time than those led by females (2014, September 26) retrieved 18 August 2019 from https://phys.org/news/2014-09-hubble-team-male-teams-telescope.html More information: Full paper: arxiv.org/abs/1409.3528 This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Researchers at the Space Telescope Science Institute (STScI) which runs the Hubble Space Telescope program, have found that there continues to be a gap between the number of projects given the go-ahead by male principle investigators (PIs) versus those headed by females. Journal information: arXiv
It is not often that you walk up to a restaurant in Delhi and bump into a queue. Unless of course, it is age-old favourites like Karim’s (the Jama Masjid outlet) or Khan Chacha. And of course there is Big Chill which continues to be a hot favourite. Of course, the Pizza Huts and McDonald’s of the world do not count. But from the queue we saw when we went to Nando’s for a review (other restaurants in the mall were pretty full too, to be fair. But none of them really had a bunch of 15-20 people waiting outside), we could safely say that the international chain, which has opened its outlet in a south Delhi mall, can be added to the list. Also Read – ‘Playing Jojo was emotionally exhausting’The place has a chirpy feel and is spread over a fairly large area. African art adorns the walls. The service is prompt and the staff is helpful. Their signature is their Peri Peri chicken which they serve in enormous quantities (a quarter plate will be more than enough for three people). You can have the juicy, tender chicken on its own or pair it with side dishes like rice to make it a complete meal. What I liked about the place is that it gives you an option to choose your spice level. So even if you are not too fond of spicy stuff, you can still enjoy a flavourful meal (because all their chicken is marinated, as the menu clearly mentions) without getting too worked up by the hot sauces. Also Read – Leslie doing new comedy special with NetflixTo some extent the place will remind you of KFC, only here you can find more options. Though it is essentially a chicken place (their international outlets are almost all about chicken), vegetarian dishes have been incorporated in the menu perhaps keeping India in mind. DETAILAt: Nando’s, 315 & 316, 2nd Floor, DLF Promenade Mall, Vasant KunjTimings: Noon to 11.30 pm Meal for two: Rs 1,000 approx
The fashion show is a part of an initiative taken by National Woman Excellence Awardees of Yog Confederation of India in association with Tihar jail and Sri creations. The initiative is aimed at developing the entrepreneurial skills of the female jail inmates to become self employed or employable.The Fashion show is to be organized on 9 March at the Constitution Club, Rafi Marg, New Delhi from 4:00 pm to 7:00 pm on the occasion of International Women’s Day. Designs and goods made at Tihar will also be exhibited as the cynosure. An one year certificate course in Fashion Designing program was launched by Vimla Mehra, IPS, DG, Tihar prisons on 7 December 2012 for the female inmates to enhance their chances of employment. Also Read – ‘Playing Jojo was emotionally exhausting’‘Efforts also will be made to arrange regular buyers of the Tihar products and to arrange sewing machines for the relieved inmates who had completed the program,’ said Laxmi Thakur Singhal, the Chairperson of National Woman Excellence Awardees.‘Companies who can employ the trained inmates will also be coordinated to make this program a successful one,’ she added.National Women Excellence Award Programme, is a venture initiated by Yog Confederation of India in association with the Ministry of Development of North Eastern Region along with other national and international organisations.